ts appetite, and has a rough, dry coat with the hairs
on end. There is moderate thirst. The respirations are somewhat
quickened and the pulse becomes rapid and full. The body temperature is
elevated, frequently reaching 104 deg. or 105 deg. F. within 36 or 48 hours from
the appearance of the first symptoms.

The visible mucous membranes, especially the conjunctivae, are of a
bright rosy red. In the lymphatic, cold-blooded, and more common horses
these symptoms of fever are less marked; even with a comparatively high
temperature the animal may retain its appetite and work comparatively
well, but these cases, if worked and overheated, are liable to develop
serious complications.

At the end of from three and a half to four days the eruption breaks
out, the fever abates, and the general symptoms improve. The eruption in
severe cases may be generalized; it may be confined to the softer skin
of the nose and lips, the genital organs, and the inside of the thighs,
or it may be localized in the neighborhood of a wound or in the
irritated skin of a pair of greasy heels. It consists of a varying
number of little nodes which, on a mucous membrane, as in the nostrils
or vagina, or on soft, unpigmented skin, appear red and feel at first
like shot under the epidermis. These nodes soften and show a yellowish
spot in the center when they become pustules. The epidermis is dissolved
and the matter escapes as a viscid fluid at first citrine and later
cloudy and purulent, which dries rapidly, forming scabs; if these fall
off or are removed they leave a little shallow, concave ulcer which
heals in the course of five or six days. In the softer skin if pigmented
the cicatrices are white and frequently remain so for about a year, when
the pigment returns. The lips or genital organs of a colored horse, if
covered with a number of small white spots about the size of a pea, will
usually indicate that the animal has been affected with the horsepox.

At times the pustules may become confluent and produce large,
superficial, serpentine ulcers on the membrane of the nostrils, around
the lips or eyelids, or on the borders of wounds and in greasy heels; in
this case the part becomes swollen, hot, painful, and is covered with a
profuse discharge of matter. In this form there is frequently a
secondary fever lasting for a day or two.

In severe cases there may be a suppurative adenitis, or inflammation of
the lymphatic glands which are fed from the aff