ed in the blood for several days, the symptoms mentioned above
may be the only ones noticed, and, as a rule, when treated with
febrifuges, the horse quickly improves in health and the appetite
returns. This condition does not last for more than a few days, when the
animal is again observed to present a dull and dejected appearance, and
on examination well-marked symptoms are found; the skin is hot, the
temperature more or less elevated--101.7 deg. to 104 deg. F.; the pulse full and
frequent--56 to 64 beats a minute; the visible mucous membranes may
appear clean, but the conjunctival membranes, especially those covering
the membrana nictitans, are usually the seat of dark-red patches of
ecchymosis, varying in size in different animals. There is more or less
thirst and slight loss of appetite; the animal eats its grain and green
grass, but leaves all or a portion of the hay with which it has been
supplied. At the same time there are slight catarrhal symptoms present,
including lacrimation and a little mucous discharge from the nostrils.
Occasionally at this period of the disease the submaxillary glands may
be found enlarged and perhaps somewhat tender on manipulation. One
symptom is markedly absent, namely, the presence of rigors or the
objective sign of chilliness. In addition, it will be noted that there
is some swelling and edema of the legs, generally between the fetlock
and the hock, which pits but is not painful on pressure, and in case of
horses there may be also some swelling of the sheath at this stage of
the disease. When the fever and concomitant symptoms have declared
themselves for a short period, one thing becomes especially noticeable
in every animal attacked, namely, the rapidity with which it loses
flesh. If the blood has been examined microscopically during the second
period of fever, at first a few parasites will have been observed in it,
which day by day increase in number and reach a maximum, where they
remain for a varying period, or at once suddenly or gradually disappear
during the period of apyrexia. After the fever and the accompanying
symptoms have for the second time been present for a few days--the
period varying from one to six--the animal is found to have lost the
dull, dejected appearance and to look bright. The temperature has fallen
and, in some cases, has attained normal or even subnormal limits. The
visible mucous membranes are clean, and the conjunctival petechiae begin
to fade; the puls