nd up the chest. During this time the wasting
has been steadily progressive, especially of the muscles of the back and
those surrounding the hip joint and the glutei.

Toward the termination of the disease it will be noticed that an animal
is disinclined to move, and when made to do so there is manifest loss of
power over the hind quarters, somewhat simulating a slight partial
paralysis, and the hind quarters of the animal reel from side to side.
In connection with this it may be noted that frequently there is
paralysis of the sphincter ani and a dilated condition of the anus.
These symptoms taken together point to some interference with the normal
functions of the spinal cord in the lower dorsal and lumbar regions, and
are probably owing to pressure caused by an exudation within the spinal
membranes. In many cases shortly before death the heart's action becomes
exceedingly violent, shaking the whole frame at each beat, so that the
sound can be heard at some distance from the animal. In some of these
cases the animal may suddenly drop dead; in others the emaciation and
weakness become so pronounced that it falls to the ground, and, after a
short struggle, succumbs to the disease. In other cases, again, the
animal falls to the ground and appears to be suffering from acute pain,
struggles violently, sweat covers the body, and respiration is very
hurried. The struggles soon exhaust the patient's strength, and for a
time it lies quiet; soon, however, the struggles commence again,
continuing until death occurs. In some cases the appetite is voracious.

The symptoms of the disease as observed in experimentally inoculated
animals are as follows: Twenty-four hours after the subcutaneous
injection of a small quantity of surra blood, in the great majority of
cases, a small circumscribed and somewhat raised swelling is noticed at
the seat of the inoculation. After forty-eight hours the tumor has
increased in size and is accompanied with some edema; it presents a
certain amount of tension of the parts involved, and is generally tender
on manipulation. These conditions continue to increase, until by the
fourth day the tumor may measure 3 or 4 inches in; one direction by 2 or
3 in the other, and raised to the extent of an inch or an inch and a
half above the surrounding tissues, or in some cases the tumor presents
an almost circular form throughout. It will be also found that, if the
tumor is firmly grasped, it is not fixed, but can