sudden exposure to cold,
it develops an acute pneumonia or other simple inflammatory trouble
which starts the latent disease and the animal has acute glanders.

In the ass, mule, and plethoric horses acute glanders usually terminates
by lobular pneumonia. In other cases the general symptoms may subside.
The symptoms of pneumonia gradually disappear, the temperature lowers,
the pulse becomes slower, the ulcers heal, leaving small, indurated
cicatrices, and the animal may return to apparent health, or may at
least be able to do a small amount of work with but a few symptoms of
the disease remaining in a chronic form. During the attack of acute
glanders the inflammation of the nasal cavities frequently spreads into
the sinuses or air cells, which are found in the forehead and in front
of the eyes on either side of the face, and causes abscesses of these
cavities, which may remain as the only visible symptom of the disease.
An animal which has recovered from a case of acute glanders, like the
animals which are affected by chronic glanders and chronic farcy, is
liable to be affected with emphysema of the lungs (heaves), and to have
a chronic cough. In this condition it may continue for a long period,
serving as a dangerous source of contagion, the more so because the
slight quantity of discharge does not serve as a warning to the owner or
driver as profuse discharge does in the more acute cases.

At the post-mortem examination of an animal which has been destroyed or
has died of glanders we find evidences of the various lesions which we
have studied in the symptoms. In addition to this, we find nodules
similar to those which we have seen on the exterior throughout the
various organs of the body. Nodules may be found in the liver, in the
spleen, and in the kidneys. We may find inflammation of the periosteum
of the bones, and we have excessive alterations in the marrow in the
interior of the bones themselves. Both these conditions during the life
of the animal may have been the cause of the lamenesses which were
difficult to diagnose.

In one case which came under the observation of the writer, a lame horse
was destroyed and found to have a large abscess of the bone of the arm,
with old nodules of the lungs. When an animal has died immediately after
an attack of a primary, acute case of glanders, we find small V-shaped
spots of acute pneumonia in the lungs. If the animal has made an
apparent recovery from acute glanders, and