in cases of chronic farcy
and chronic glanders, no matter how few the external and visible
symptoms may have been, there is a deposit of nodules--small, hard,
indurated nodes--of new connective tissue to be found in the lungs. When
these have existed for some time we may find a deposit of lime salts in
them. These indurated nodules retain the virus and their power to give
out contagion for almost an indefinite time, and predispose to the
causes which we have studied as the common factors in developing a
chronic case into an acute case; that is, an inflammatory process wakens
their vitality and produces a reinfection of the entire animal. The
blood of an animal suffering from chronic glanders and farcy is not
virulent and is unaltered, but during the attack of acute glanders,
while the animal has fever, the blood becomes virulent and remains so
for a few days.

_Treatment._--Almost the entire list of drugs in the pharmacopoeia has
been tested in the treatment of glanders. Good hygienic surroundings,
good feed, with alteratives and tonics, frequently ameliorate the
symptoms, and often do so to such an extent that the animal would pass
the examination of any expert as a perfectly sound animal. While in this
case the number of nodules of the lungs, which are invariably there, may
be so few as not to cause sufficient disturbance in the respiration as
to attract the attention of the examiner, yet they exist, and will
remain there almost indefinitely, with the constant possibility of a
return of acute symptoms.

It is probable that some horses may recover from glanders if the
infection is slight, but it will not do to depend upon this except under
the most stringent veterinary supervision. With good care, good feed,
good surroundings and little work, an animal affected with glanders may
live for months or even years in a state of apparently perfect health,
but with the first deprivation of feed, with a few days of severe hard
work, with exposure to cold or with the attack of a simple fever or
inflammatory trouble from other causes, the latent seeds of the disease
break out and develop the trouble again in an acute form.

In several celebrated cases horses which have been affected with
glanders have been known to work for years and die from other causes
without ever having had the return of symptoms; but allowing that these
cases may occur, they are so few and far between, and the danger of
infection of glanders to other ho