r the care of the writer a horse, four weeks after being
bitten on the forearm by a rabid dog, developed local irritation in the
healed wound and tore it with its teeth into a large ulcer. This was
healed by local treatment in 10 days, and the horse was kept under
surveillance for more than a month. On the advice of another
practitioner the horse was taken home and put to work; within 3 days it
developed violent symptoms and had to be destroyed.

_Diagnosis._--The diagnosis of rabies in the horse is to be made from
the various brain troubles to which the animal is subject; first by the
history of a previous bite of a rabid animal or inoculation by other
means; second, by the evident volition and consciousness on the part of
the animal in its attacks, offensive and defensive, on persons, animals,
or other disturbing surroundings. The irritation and reopening of the
original wound or point of inoculation is a valuable factor in
diagnosis. Diagnosis after death may be made by microscopic examination
for Negri bodies or by the inoculation of rabbits, as already mentioned.

Recovery from rabies may be considered as a question of the correctness
of the original diagnosis. Rabies is always fatal.

_Treatment._--No remedial treatment has ever been successful. All the
anodynes and anesthetics, opium, belladonna, bromid of potash, ether,
chloroform, etc., have been used without avail. The prophylactic
treatment of successive inoculations is being used on human beings, and
has experimentally proved efficacious in dogs, but would be
impracticable in the horse unless the conditions were quite exceptional.

DOURINE.

By JOHN R. MOHLER, V. M. D., _Assistant Chief, Bureau of Animal
Industry_.

Dourine (also known as maladie du coit, equine syphilis, covering
disease, breeding paralysis) is a specific infectious disease affecting
under normal conditions only the horse and ass, transmitted from animal
to animal by the act of copulation, and due to an animal parasite, the
_Trypanosoma equiperdum_.

_History._--It is described as having existed as early as 1796 in the
Eastern Hemisphere, and was more or less prevalent in several of the
European countries, including France, Germany, Austria, and Switzerland,
during the first half of the nineteenth century. Its presence was
recognized for the first time in the United States in 1886, when an
outbreak occurred in Illinois. Since then the existence of the disease
has been observed at