rognosis._--The prognosis of the disease is very unfavorable.
Veterinarians in different sections of the country where it is prevalent
report a mortality of 75 per cent or even higher. Recovery takes place
only when treatment is begun early or when the animal has a long
convalescent period.

_Treatment._--The treatment of the disease has so far been far from
satisfactory. The iodid, permanganate, and carbonate of potash have been
used. Arsenic, axytol, quinin, and silver preparations have been
suggested, but all have been uniformly without success. Intestinal
antiseptics have been resorted to, and the results are encouraging but
not altogether satisfactory. Symptomatic treatment seems to be the most
dependable. For instance, Davison, of this bureau, was able to reduce
greatly the mortality from this affection by giving an antipyretic of 40
grains of quinin, 2 drams of acetanilid, and 30 grains of powdered nux
vomica four times daily. In the late stages, with weak heart action,
alcohol should be substituted for acetanilid. Cold-water sponge baths
may be given, and in addition frequent copious injections of cold water
per rectum, which has a beneficial effect in reducing the temperature
and in stimulating peristalsis of the bowels, which, as a result of the
disease, show a tendency to become torpid during the fever. Purgatives,
on account of their debilitating effect, should not be given unless
absolutely necessary, but laxatives and easily digested feeds should be
given instead. Not infrequently a dirty yellowish tinge of the visible
mucous membranes has been observed, in which cases 20 grains of calomel
in from 2 to 4 drams of aloes in a ball, or 2-dram doses of fluid
extract of podophyllin, may be given. Following the subsidence of the
fever, a tonic should be administered, composed of the following drugs
in combination:

Arsenious acid grams 2
Powdered nux vomica do 28
Powdered cinchona bark do 85
Powdered gentian root do 110

These should be well mixed and one-half teaspoonful given to the
affected animal at each feed.

As in the case of all other infectious diseases, the healthy should be
separated from the sick horses and thorough disinfection of the infected
stables, stalls, litter, and stable utensils should be carried out in
order to prevent the recurrence of the disease. As a disinfectant the
compound solution of cresol, carbolic acid, or