up, belly, and neck.

The intensity of the symptoms mentioned which are significant of the
early stage of the disease may vary to a wide extent and in many
instances be so mild as to escape the attention of any but the most
careful observer. They commonly disappear after a brief period. The
apparent recovery, however, is not permanent, for such animals after a
period of variable length manifest constitutional or nervous symptoms.
These may not appear for several months or even years. They consist of a
general nervous disorder with staggering, swaying gait, especially in
the hind limbs. The animal generally becomes emaciated, the abdomen
assuming a tucked-up appearance. The first indication of paralysis will
be noted in traveling, when the animal fails to pick up one of the hind
feet as freely as the other, or both may become affected at the same
time, at which time knuckling is a common symptom. Labored breathing is
occasionally noted. When the paralysis of the hind limbs starts to
appear the disease usually progresses rapidly. The horse goes down, is
unable to rise, and dies in a short time from nervous exhaustion. The
appetite usually remains good up to the last.

Although a case of dourine may now and then recover, as a rule the
disease is present in the latent stage. Bad weather, exposure,
insufficient feed, and complicating diseases like influenza, distemper,
or in fact any condition which tends to lower the vitality of the
animal, may hasten the termination of the disease.

_Diagnosis._--The complement-fixation test furnishes by far the most
reliable means of diagnosis and is especially valuable in a chronic
affection of this character, when the symptoms manifested are variable
and frequently so obscure as to escape observation. This is a laboratory
test requiring special facilities and the services of a trained
bacteriologist.

_Treatment._--Little benefit can be obtained from medicinal treatment,
nor is such treatment desirable in this country, where the disease has
existed only in restricted areas, and where sanitary considerations
demand its prompt eradication.

INFECTIOUS ABORTION IN MARES.

Infectious abortion (also known as contagious abortion, epizootic
abortion, enzootic abortion, slinking of colts) is a disease of mares
which from a specific cause results in the premature expulsion of the
fetus and its membranes from the uterus. It is characterized by an
inflammatory condition of the female repr