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infected. _Symptoms._--The symptoms of anthrax usually develop with extreme rapidity. The horse is dejected and falls into a state of profound stupor, attended with great muscular weakness. The feeble, indolent animal, if forced to move, drags its legs. There are severe chills, agitation of the muscles, symptoms of vertigo, and at times colicky pains. The mucous membranes turn a deep ocher or bluish-red color. The body temperature is rapidly elevated to 104 deg. or 105 deg. F. The breathing is increased to 30 or 40 respirations in the minute and the pulse is greatly accelerated, but while the arteries are soft and almost imperceptible, the heart beats can be felt and heard, violent and tumultuous. In some cases, when inoculation is through the skin, large subcutaneous swellings appear; these may involve a leg, a shoulder, one side of the body, or the neck or head. The swelling is at first hot and painful, but afterwards it becomes necrotic and sensation is lost. The symptoms last but two, three, or four days at most, when the case usually terminates fatally. An examination of the blood shows a dark fluid which will not clot, and which remains black after exposure to the air. After death the bodies putrefy rapidly and bloat up; the tissues are filled with gases, and a bloody foam exudes from the mouth, nostrils, and anus, and frequently the mucous membranes of the rectum protrude from the latter. The hairs detach from the skin. Congestion of all the organs and tissues is found, with interstitial hemorrhages. The muscles are friable and are covered with ecchymotic spots. This is especially marked in the heart. The black, uncoagulated, and incoagulable blood shows an iridescent scum on its surface, which is due to the fat of the animal dissolved by the ammonia produced by the decomposed tissues. The serum oozes out of every tissue and contains broken-down blood, which, when examined microscopically, is found to have the red globules crenated and the leucocytes granular. A high power of the microscope also reveals the bacteria in the shape of little rodlike bodies of homogeneous texture with their brilliant spores. The lymphatic ganglia are increased four, five, six, or ten times their natural size, enlarged by the engorgement of blood. The spleen shows nodulated black spots containing a muddy blood, which is found teeming with the virus. This organ is much enlarged and is quite friable. The mucous membranes of the in
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