year before.

Public watering troughs and the feed boxes of boarding stables and the
tavern stables of market towns are among the most common recipients for
the virus of glanders, which is most dangerous in its fresh state, but
cases have been known to be caused by feeding animals in the box or
stall in which glandered animals had stood several months before. While
the discharge from a case of chronic glanders is much less liable to
contain many active bacilli than that from a case of acute glanders, the
former, if it infects an animal, will produce the same disease as the
latter. It may assume from the outset an acute or chronic form,
according to the susceptibility of the animal infected, and this does
not depend upon the character of the disease from which the virus was
derived.

The animals of the genus _Equus_--the horse, the ass, and the mule--are
those which are the most susceptible to contract glanders, but in these
we find a much greater receptivity in the ass and mule than we do in the
horse. In the ass and mule in almost all cases the period of incubation
is short and the disease develops in an acute form. We find that the
kind of horse infected has an influence on the character of the disease;
in full-blooded, fat horses of a sanguinary temperament, the disease
usually develops in an acute form, while in the lymphatic, cold-blooded,
more common race of horses the disease usually assumes a chronic form.
If the disease develops first in the chronic form in a horse in fair
condition, starvation and overwork are liable to bring on an acute
attack, but when the disease is inoculated into a debilitated and
impoverished animal it is apt to start in the latent form. Inoculation
on the lips or the exterior of the animal is frequently followed by an
acute attack, while infection by ingestion of the virus and inoculation
by means of the digestive tract is often followed by the trouble in the
chronic latent form.

In the dog the inoculation of glanders may develop a constitutional
disease with all the symptoms which are found in the horse, but more
frequently the virus pullulates only at the point of inoculation,
remaining for some time as a local sore, which may then heal, leaving a
perfectly sound animal; but while the local sore is continuing to
ulcerate, and specific virus exists in it, it may be the carrier of
contagion to other animals. In man we find a greater receptivity to
glanders than in the dog, and in ma