Wordsworth presented to the Medical Society of London six members of
one family, all of whom had congenital displacement of the crystalline
lens outward and upward. The family consisted of a woman of fifty, two
sons, thirty-five and thirty-seven, and three grandchildren--a girl of
ten and boys of five and seven. The irides were tremulous.

Clark reports a case of congenital dislocation of both crystalline
lenses. The lenses moved freely through the pupil into the anterior
chambers. The condition remained unchanged for four years, when
glaucoma supervened.

Differences in Color of the Two Eyes.--It is not uncommon to see people
with different colored eyes. Anastasius I had one black eye and the
other blue, from whence he derived his name "Dicore," by which this
Emperor of the Orient was generally known. Two distinct colors have
been seen in an iris. Berry gives a colored illustration of such a case.

The varieties of strabismus are so common that they will be passed
without mention. Kuhn presents an exhaustive analysis of 73 cases of
congenital defects of the movements of the eyes, considered clinically
and didactically. Some or all of the muscles may be absent or two or
more may be amalgamated, with anomalies of insertion, false, double, or
degenerated, etc.

The influence of heredity in the causation of congenital defects of the
eye is strikingly illustrated by De Beck. In three generations twelve
members of one family had either coloboma iridis or irideremia. He
performed two operations for the cure of cataract in two brothers. The
operations were attended with difficulty in all four eyes and followed
by cyclitis. The result was good in one eye of each patient, the eye
most recently blind. Posey had a case of coloboma in the macular
region in a patient who had a supernumerary tooth. He believes the
defects were inherited, as the patient's mother also had a
supernumerary tooth.

Nunnely reports cases of congenital malformation in three children of
one family. The globes of two of them (a boy and a girl) were smaller
than natural, and in the boy in addition were flattened by the action
of the recti muscles and were soft; the sclera were very vascular and
the cornea, conical, the irides dull, thin, and tremulous; the pupils
were not in the axis of vision, but were to the nasal side. The elder
sister had the same congenital condition, but to a lesser degree. The
other boy in the family had a total absence of iride