us deposit, extending at times over the tongue
and occasionally a little way down the trachea. The lungs are normal,
except from complications following drenching or recumbence for a long
period. The heart is usually normal in appearance, except an occasional
cluster of hemorrhagic points on the outer surface, while the blood is
dark and firmly coagulated. The lining of the stomach indicates a
subacute gastritis, while occasionally an erosion is noted. An edema is
observed in the submucosa of such cases. The first few inches of the
small intestines likewise may show slight inflammation in certain cases,
while in others it is quite severe; otherwise the digestive tract
appears normal, excluding the presence of varying numbers of bots,
_Strongylus vulgatus_, and a few other nematodes. The liver is congested
and swollen in some cases, while it appears normal in others. The spleen
is, as a rule, normal, and at times the kidneys are slightly congested.
The bladder is often distended with dark-colored urine, and occasionally
a marked cystitis has been observed. The adipose tissue throughout the
carcass may show a pronounced icteric appearance in certain cases. On
removing the bones of the skull the brain appears to be normal
macroscopically in a few instances, but in most cases the veins and
capillaries of the meninges of the cerebrum, cerebellum, and
occasionally the medulla is distinctly dilated and engorged, and in a
few cases there are pronounced lesions of a leptomeningitis. An
excessive quantity of cerebrospinal fluid is present in most of the
cases. On the floor of the lateral ventricles of several brains there
was noted a slight softening caused by hemorrhages into the brain
substance. There is always an abundance of fluid in the subarachnoid
spaces, ventricles, and at the base of the brain, usually of the color
of diabetic urine, and containing a limited number of flocculi, but in a
few cases it was slightly blood tinged. The spinal cord was not found
involved in the few cases examined.

_Treatment._--One attack of the disease does not confer immunity. Horses
have been observed which have recovered from two attacks, and still
others that recovered from the first but died as a result of the second
attack.

Inasmuch as a natural immunity does not appear after an attack of
cerebrospinal meningitis, it might be anticipated that serum of
recovered cases would possess neither curative nor prophylactic
qualities. Neverthe