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atter stage of the disease, and may cause renewed paroxysms. The muscles of the limbs or back may be subject to intermittent spasms, or spasmodic tremors; finally, the hind limbs become paralyzed, breathing very difficult, and convulsions supervene, followed by death. The pulse and respirations are increased in frequency from the outset of the attack. Rabies may possibly be mistaken for tetanus. In the latter disease we find tonic spasms of the muscles of the jaws, or stiffness of the neck or back very early in the attack, and evidence of viciousness is absent. _Treatment._--As soon as the true nature of the disease is ascertained the animal should be killed. _Prevention._--When a horse is known to have been bitten by a rabid animal, immediate cauterization of the wound with a red-hot iron may possibly destroy the virus before absorption of it takes place. PLUMBISM, OR LEAD POISONING. This disease is not of frequent occurrence. It may be due to the habitual drinking of water which has been standing in leaden conductors or in old paint barrels, etc. It has been met with in enzootic form near smelting works, where, by the fumes arising from the works, lead in the form of oxid, carbonate, or sulphate was deposited on the grass and herbage which the horses ate. _Symptoms._--Lead poisoning produces derangement of the functions of digestion and locomotion, or it may affect the lungs principally. In whatever system of organs the lead is mostly deposited there we have the symptoms of nervous debility most manifest. If in the lungs, the breathing becomes difficult and the animal gets out of breath very quickly when compelled to run. Roaring, also, is very frequently a symptom of lead poisoning. When it affects the stomach, the animal gradually falls away in flesh, the hair becomes rough, the skin tight, and colicky symptoms develop. When the deposit is principally in the muscles, partial or complete paralysis gradually develops. When large quantities of lead have been taken in and absorbed, symptoms resembling epilepsy may result, or coma and delirium develop and prove fatal. In lead poisoning there is seldom any increase in temperature. A blue line forms along the gums of the front teeth, and the breath assumes a peculiarly offensive odor. Lead can always be detected in the urine by chemical tests. _Treatment._--The administration of 2-dram doses of iodid of potassium three times a day is indicated. This will for
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