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scles are caused to contract more vigorously, increasing their working power without there being any secondary reaction leading to a diminished capacity for work. Its action upon the circulation is somewhat antagonistic; for while it tends to increase the rate of the heart by acting directly on the heart muscle, it tends to decrease it by stimulating the inhibitory center in the medulla.[188] The effect on the kidneys is more marked, the diuretic effect being shown by an increase in water, soluble solids, and of uric acid directly attributable to the caffein content of the coffee taken. In the alimentary tract coffee seems to stimulate the oxyntic cells and slightly to increase the secretion of hydrochloric acid, as well as to favor intestinal peristalsis. It is difficult to accept reports of coffee accomplishing both a decrease in metabolism and an increase in body heat; but if the production of heat by the demethylation of caffein to form uric acid and a possible repression of perspiration by coffee be considered, the simultaneous occurrence of these two physiological reactions may be credited. The disagreement of medical authorities over the physiological effects of coffee is quite pronounced. This may be observed by a careful perusal of the following statements made by these men. It will be noticed that the majority opinion is that coffee in moderation is not harmful. Just how much coffee a person may drink, and still remain within the limits of moderation and temperance, is dependent solely upon the individual constitution, and should be decided from personal experience rather than by accepting an arbitrary standard set by some one who professes to be an authority on the matter. A writer in the _British Homeopathic Review_[189] says that "the exciting effects of coffee upon the nervous system exhibit themselves in all its departments as a temporary exaltation. The emotions are raised in pitch, the fancies are lively and vivid, benevolence is excited, the religious sense is stimulated, there is great loquacity.... The intellectual powers are stimulated, both memory and judgment are rendered more keen and unusual vivacity of verbal expression rules for a short time." He continues: Hahnemann gives a characteristically careful account of the coffee headache. If the quantity of coffee taken be immoderately great and the body be very excitable and quite unused to coffee, there occurs a semilat
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