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rative evidence of the existence of cytoplasmic organ-forming stuffs has been supplied for several other species, _e.g._, _Patella_ (Wilson), _Cynthia_ (Conklin), _Cerebratulus_ (Zeleny), and _Echinus_ (Boveri). It is interesting to recall that so long ago as 1874 W. His[504] put forward the theory that there exist in the blastoderm and even in the egg prelocalised areas, which contain the formative material for each organ of the embryo, and from which the embryo is developed by a simple process of unequal growth. The experimental study of form was prosecuted in many other directions besides that of experimental embryology. The study of regeneration and of regulatory processes attracted many workers, among whom may be mentioned T. H. Morgan, C. M. Child, and H. Driesch. In an interesting series of papers C. Herbst applied the principles of the physiology of stimulus to the interpretation of development.[505] The formative power of function was studied in Germany by Roux and his pupils, Fuld, O. Levy, Schepelmann and others, particularly by E. Babak. In France, F. Houssay inaugurated[506] an important series of memoirs by himself and his pupils on "dynamical morphology," the most important memoir being his own valuable discussion of the functional significance of form in fishes.[507] The principles of his dynamical morphology were first laid down in his book _La Forme et la Vie_ (1900). The famous experiments of Loeb, Delage and others on artificial parthenogenesis may also be mentioned, though their connection with morphology is somewhat remote. The period was characterised also by the lively discussion of first principles, in which Driesch took a leading part. Materialistic methods of interpretation were upheld by perhaps the majority of biologists, but vitalism found powerful support. [464] See Carus's remark, referred to on p. 194, above. [465] Roux, _Die Entwicklungsmechanik_, p. 26, Leipzig, 1905. [466] T. H. Morgan, _Regeneration_, p. 1, New York and London, 1901. [467] _Recherches sur la production artificielle des Monstruosites_, Paris, 1877, and many later papers. [468] _Unsere Koerperform und das physiologische Problem ihrer Entstehung_, Leipzig, 1874. [469] J. W. Jenkinson, _Experimental Embryology_, p. 3, Oxford, 1909. [470] "Ueber die Verzweigungen der Blutgefaesse des Menschen," _Jen. Zeit_., xii., 1878. [471] "Ueber die B
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