exert a beneficial influence, in
small doses. None of the preparations of mercury should be taken
internally without the advice of a skillful physician, therefore, we
shall not give their doses.

THE COMPOUNDING OF ALTERATIVES.

The efficacy of this class of remedies can be greatly increased by
properly combining several of them into one compound.

This requires a knowledge of Pharmaceutical Chemistry; i.e., the
preparation of compounds founded on the chemical relation and action of
their several remedial, active principles. Many practitioners make
combinations of remedies which neutralize each other's influence,
instead of extending their efficacy and curative power.

DR. PIERCE'S "GOLDEN MEDICAL DISCOVERY," or Alterative Extract. This
compound is a highly nutritive and tonic preparation, combining the
remedial properties of the best vegetable alteratives at present known
to the medical profession. In perfecting this alterative compound, and
likewise other standard preparations of medicine, we have made an outlay
of many thousand dollars for chemical apparatus, and special machinery
by the aid of which these remedies have been brought to their present
perfection. Great pains are taken to obtain the materials at the right
season of the year, properly cured so that none of their remedial
qualities may be impaired. We, therefore, can with great confidence
recommend Dr. Pierce's "Golden Medical Discovery" as one of the best
preparations of the alterative class. Like all others of this type, its
action is insensible, producing gradual changes, arousing the excretory
glands to remove morbid materials, and at the same time toning the
secretory organs. The manufacture of this compound is under the special
supervision of a competent chemist and pharmaceutist, and it is now put
up in bottles wrapped with full directions for its use. We can
confidently recommend this compound whenever an alterative is required
to cleanse the blood, tone the system, increase its nutrition, and
establish a healthy condition. For these reasons we shall often advise
its employment.

DR. PIERCE'S PLEASANT PURGATIVE PELLETS. These pellets combine the pure,
concentrated, active principles of several vegetable alteratives, and
the result is, that within the small compass of a few grains he has most
happily blended and chemically condensed these properties so that their
action upon the ANIMAL ECONOMY is sanative and universal. They awaken
the la