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ls of pipe which build a furnace, or the stones and mortar which make the support of a great railroad bridge. Yet while the principles of structure are thus simple, for the general understanding by the student who begins their study the complete appreciation of the shades of variation, which differentiate one tissue from another, which define a sound tendon or a ligament from a fibrous band--the result of disease filling in an old lesion and tying one organ with another--is as complicated as the nicest jointing of Chinese woodwork, the building of a furnace for the most difficult chemical analysis, or the construction of a bridge which will stand for ages and resist any force or weight. All tissues are composed of certain fundamental and similar elements which are governed by the same rules of life, though at first glance they may appear to be widely different. These are (a) amorphous substances, (b) fibers, and (c) cells. (a) Amorphous substances may be in liquid form, as in the fluid of the blood, which holds a vast amount of salts and nutritive matter in solution; or they may be in a semiliquid condition, as the plasma which infiltrates the loose meshes of connective tissue and lubricates the surface of some membranes; or they may be in the form of a glue or cement, fastening one structure to another, as a tendon or muscle end to a bone; or, again, they hold similar elements firmly together, as in bone, where they form a stiff matrix which becomes impregnated with lime salts. Amorphous substances, again, form the protoplasm or nutritive element of cells or the elements of life. (b) Fibers are formed of elements of organic matter which have only a passive function. They can be assimilated to little strings, or cords, tangled one with another like a mass of waste yarn, woven regularly like a cloth, or bound together like a rope. They are of two kinds--white connective tissue fibers, only slightly extensible, pliable, and very strong, and yellow elastic fibers, elastic, curly, ramified, and very dense. These fibers once created require the constant presence of fluids around them in order to retain their functional condition, as a piece of harness leather demands continual oiling to keep its strength, but they undergo no change or alteration in their form until destroyed by death. (c) Cells, which may even be regarded as low forms of life, are masses of protoplasm or amorphous living matter, with a nucleus and fre
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