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laboratory, who will have nothing but syllogistic deductions and quantitative determinations based upon animal experiments as the data of their science, will be apt to look askance upon the preceding paragraphs, and those which will follow. To them, any man who relates the internal secretions to anything, outside of the routineer's paths, puts his reputation at stake, if he has any reputation at all to start in with. They would have us deliver a Scotch verdict upon all the questions which arise as soon as one attempts to take in the more general significance of the glands of internal secretion. This, even though the more general implications concerning the effects of their products, the relations of them to growth and development, nutrition and energy, environmental reactions and resistance to disease, as well as the grand complex of intelligence, are admittedly well ascertained in some directions. The method of absolute measurement in science has yielded miracles. For some thousands of years, an isolated individual, here and there or an isolated institution have devoted themselves to the task, struggling not only with their own weaknesses, but with religious and political dogmas which spoiled and vitiated even the beginnings of their efforts. When, in the seventeenth century, men associated themselves in research, for free communication and discussion of their findings, a great invention came alive. Close on its heels was born the exact experimental method. Amazing triumphs were born of that marriage which swept away before it ignorance and superstition and prejudice. Its children and grandchildren have flourished and grown strong and mighty. They have transmuted the material conditions of life. Certainly all the laurels belong to the method of absolute, measured observations. Yet all this time the old method of inductive observation has not gone dead. Most magnificent triumph of nineteenth century science, the evolution theory of Charles Darwin, remains the most conspicuous instance of clarification of thought in human history. That work was the outcome of an attempt to relate and interpret a collection of observations on species and their variations, that had long lain to hand, a mixture without a solvent. Darwin saw certain generalizations as solvents, and behold! a clear solution out of the mud. But it was by piling evidence upon evidence, co-ordinating isolated facts not directly associated, that the towering
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