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ize of the larynx, the emotions to which our exterior gives expression. All are to a certain extent conditioned by the productivity of our glands of internal secretion." (Llewellys F. Barker, Johns Hopkins University, 1st President of Association for Study of Internal Secretions.) The implications for the statesman, the educator, the vocational expert, the student of the neurotic and of genius, of delinquents, deficients and criminals, the explorers of the exceptional and the commonplace, the understanding of the poetic and kinetic, base and dull types, as well as of those two master interests of mankind, Sex and War, are manifest. The mystery of the individual, in all his distinct uniqueness, begins to be penetrated. And so every phase of social life, in which the individual is at bottom the final determinant, must be reviewed in the light of the new knowledge. History may be examined from an entirely new angle. The biographies of our Heroes of the Past, in the Carlylean sense, will bear reinspection. Even Utopias will have to be revised. The internal secretions constitute and determine much of the inherited powers of the individual and their development They control physical and mental growth and all the metabolic processes of fundamental importance. They dominate all the vital functions during the three cycles of life. They co-operate in an intimate relationship which may be compared to an interlocking directorate. A derangement of their function, causing an insufficiency of them, an excess, or an abnormality, upsets the entire equilibrium of the body, with transforming effects upon the mind and the organs. In short, they control human nature, and whoever controls them, controls human nature. The control of the glands of internal secretion waits upon our knowledge of them, the nature and precise composition of the substances manufactured by them, and just what they do to the cells. Envisaging the future, that knowledge today is meagre. Looking back fifty years, it becomes an amazing achievement and revelation. It is worth our while to survey the accomplished, and to trace its general human significance. For a certain tangible degree of knowledge and control has been attained and should be part of the average citizen's equipment in dealing with the everyday problems of his life. THE ATTITUDE OF THE LABORATORY A certain number of so-called experimental physiologists, that is, the physiologists of the animal
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