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e it in a test-tube, indeed to possess it in large quantities in bottles, to be able to manipulate and examine it without fear of the co-action of admixed impurities, to see it with the eye, and to taste it with the tongue, was truly a marvel. The miracle aroused at once scores of researches. THE GLAND OF COMBAT AND FIGHT Considering its effects, one is reminded at once of the similarity to the expression of a primitive emotion like anger or fear. So, by turning a relation upside down, it was argued that if artificial adrenalin could produce all these effects of an emotion like fear, the emotion itself should produce an increase of the natural adrenalin in the blood. This was found to be the case. Cannon of Harvard has built up an entire theory of the adrenal as the gland of emergencies upon the basis of these effects. In the facing of crises the adrenal functions as the gland of combat. And indeed, as I have mentioned, the more combative and pugnacious an animal, the more adrenal it has, while the timid and meek and weak have less. The Glands of Combat, the glands of emergency energy, the glands of preparedness,--such are the adrenal glands when viewed from the adrenalin standpoint. A picture of its activity in the evolutionary scheme of struggle and survival is something like the following: meeting an enemy, the animal is put in danger. It must fight or flee for its life. In either case, certain conditions must be fulfilled, if the body of the animal endangered is to be saved. To prevent injury to itself, and to do as much injury as possible to the foe--that becomes its immediate urge and necessity. Of the two animals, if in one the heart should begin to beat more strongly, the blood pressure to rise, the blood to flow more rapidly through the attacking instruments, the muscles, the teeth and claws, the brain and its eyes, while the other animal experiences none of these, the former will be the victor in fight or flight. Adrenalin may be looked upon as the invention for the mobilization at a moment's notice, or as we say, after generations of use, by instinct, of all these visceral and blood advantages in the struggle of combat or flight. The nature of instinct, in its relation to the glands of internal secretion, is a problem for another chapter. But we may note that the James-Lange theory of an emotion regards it as a consciousness of the very changes in the organism adrenalin causes. Since adrenalin is the
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