ch Evening, Night, and Morning
for a Remission, and then immediately to fly to the Bark, as
the only Remedy that could avert the Danger. If the Patient
was strong, he gave Half an Ounce of the Bark, with six
Drachms of the _sal catharticum amarum_, divided into four
equal Parts, of which the Patient took one every two Hours;
the Effect of which was, that the next Fit was mitigated, and
an Intermission commonly ensued, in which the Bark was
repeated without the Purgative, to finish the Cure.--But
where the Patient was excessively feeble, and there was a
manifest Risk of his dying in next Fit, he gave Cordials with
the Bark, instead of the _sal catharticum_; and endeavoured
to throw in six or seven Drachms in the Space of ten or
twelve Hours; he having found by Experience, that if a
smaller Quantity is given, the Paroxysms come on earlier than
usual, and make all Attempts to preserve Life unsuccessful.
See his _Account of the epidemic Diseases of Minorca_, cap.
iii. 2d edit. p. 192.

In _England_, Vernal, Quotidian, and Tertian Agues, frequently go off
after Bleeding, and taking some Emetics and Purges, and the saline
Draughts, and cooling Medicines, for some Time, without the Use of the
Bark; but in _Germany_ very few yielded to this Treatment, and we were
obliged to give the Bark[83] before we could put a Stop to them.

[83] Sometimes, when Patients are reduced low by Agues, the
Stomach becomes so squeamish as to reject the Bark in every
Shape it can be given; in such Cases, when the Ague cannot be
stopped by other Means, it may be administered with great
Advantage in Clysters, of which the following is a very
remarkable Instance.--_William Hadderell_, a Lad seventeen
Years of Age, in the End of the Year 1761, was attacked with
a severe Tertian Ague, in which a Mortification came on his
left Foot, and one-half of it dropt off; notwithstanding, his
Ague continued to attack him every second Day, and the Sore
continued running on the 12th of _October_ 1763, when he was
admitted into _St. George_'s Hospital. He was reduced
extremely low; and the Sore of his Foot looked so bad, that
it was at first imagined he must lose his Leg. He was ordered
some Vomits, and a Purge, and cooling Medicines, and
afterwards to take the Bark freely; but his Stomach rejected
it, in whatever Form it was give