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superfluous nourishment becomes an homogeneous body, which is then changed by successive transformations into an animal. Digby is frankly deterministic in his description of embryonic development: Take a beane, or any other seede, and putt it into the earth, and lett water fall upon it; can it then choose but that the beane must swell? The beane swelling, can it choose but breake the skinne? The skinne broken can it choose (by reason of the heate that is in it) but push out more matter, and do that action which we may call germinating.... Now if all this orderly succession of mutations be necessarily made in a beane, by force of sundry circumstances and externall accidents; why may it not be conceived that the like is also done in sensible creatures; but in a more perfect manner.... Surely the progresse we have sett downe is much more reasonable, then to conceive that in the meale of the beane, are contained in litle, severall similar substances.... Or, that in the seede of the male, there is already in act, the substance of flesh, of bone, of sinewes, of veines, and the rest of those severall similar partes which are found in the body of an animall; and that they are but extended to their due magnitude, by the humidity drawne from the mother, without receiving any substantiall mutation from what they were originally in the seede. Lett us then confidently conclude, that all generation is made of a fitting, but remote, homogeneall compounded substance: upon which, outward Agents working in the due course of nature, do change it into an other substance, quite different from the first, and do make it lesse homogeneall then the first was. And other circumstances and agents, do change this second into a thirde; that thirde, into a fourth; and so onwardes, by successive mutations (that still make every new thing become lesse homogeneall, then the former was, according to the nature of heate, mingling more and more different bodies together) untill that substance be produced, which we consider in the periode of all these mutations....[10] Digby thus makes a good statement of epigenetic development. He attempts, without success, a physiochemical explanation of the mechanisms of development, finally admitting: I persuade my selfe it appeareth evident enough, that to effec
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