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ut any surrounding sac to protect the surrounding structures from its destructive action, and without the usual disposition of pus to advance harmlessly toward the surface and escape; and, finally, by a low, prostrating type of fever, with elevated temperature of the body, coated tongue, excited breathing, and loss of appetite. The pus when escaping through a lancet wound is grayish, brownish, or reddish, with a heavy or fetid odor, and inter-mixed with shreds of broken-down tissues. The most destructive form, however, is that in which pus is deficient and gangrene and sloughing more speedy and extensive. _Treatment_ resolves itself mainly into the elimination from the system of the poisonous products of the bacteria by laxatives and diuretics, the sustaining of the failing vitality by tonics and stimulants, above all those of the nature of antiferments, and the local application of astringent and antiseptic agents. Internal treatment may consist in 4 drams tincture of muriate of iron and one-half dram muriate of ammonia or chlorate of potash, given in a pint of water every two hours. To this may be added, liberally, whisky or brandy when the prostration is very marked. Locally a strong solution of iron, alum, or of sulphate of iron and laudanum may be used; or the affected part may be painted with tincture of muriate of iron or with iodized phenol. In mild cases a lotion of 4 drams sugar of lead and 2 ounces laudanum in a quart of water may be applied. It is desirable to avoid the formation of wounds and the consequent septic action, yet when pus has formed and is felt by fluctuation under the finger to be approaching the surface it should be freely opened with a clean, sharp lancet, and the wound thereafter disinfected daily with carbolic acid 1 part to water 10 parts, with a saturated solution of hyposulphite of soda, or with powders of iodoform or salol. HORSEPOX, ANTHRAX, AND CUTANEOUS GLANDERS (FARCY). These subjects are discussed under the head of contagious diseases. CALLOSITIES. These are simple thickening and induration of the cuticle by reason of continued pressure, notably in lying down on a hard surface. Being devoid of hair, they cause blemishes; hence, smooth floors and good bedding should be provided as preventives. HORNY SLOUGHS (SITFASTS), OR SLOUGHING CALLOSITIES. These are circumscribed sloughs of limited portions of the skin, the result of pressure by badly fitting harness or by
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