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weekly illustrated Spiritual journal. $2.50 per annum, published at San Francisco, is now in its fourth volume, and has obtained a merited success. THE TRUTH-SEEKER, a weekly journal ($3 a year) established by the late D. M. Bennett, still carries on with undiminished ability the honest agnostic work for which it has been famous. It is a vigorous iconoclast but does little for constructive progress. THE OPEN COURT, by B. F. Underwood, Chicago, with an able corps of correspondents, maintains a high literary character, and discusses philosophy and current topics from the agnostic standpoint. Its belief in dry metaphysics, and its stubborn materialistic scepticism are its greatest peculiarities. Published fortnightly at $3 a year. UNLIKE ANY OTHER PAPER. The _Spectator_, unlike other home papers, seeks (1) to acquaint every family with simple and efficient treatment for the various common diseases, to, in a word, educate the people so they can avoid disease and cure sickness, thus saving enormous doctors' bills, and many precious lives. (2) To elevate and cultivate the moral nature, awakening the conscience, and developing the noblest attributes of manhood. (3) To give instructive and entertaining food to literary taste, thus developing the mind. (4) To give just such hints to housekeepers that they need to tell how to prepare delicious dishes, to beautify homes, and to make the fireside the most attractive spot in the world.--_Am. Spectator_. MAYO'S ANAESTHETIC. The suspension of pain, under dangerous surgical operations, is the greatest triumph of Therapeutic Science in the present century. It came first by mesmeric hypnotism, which was applicable only to a few, and was restricted by the jealous hostility of the old medical profession. Then came the nitrous oxide, introduced by Dr. Wells, of Hartford, and promptly discountenanced by the enlightened (?) medical profession of Boston, and set aside for the next candidate, ether, discovered in the United States also, but far interior to the nitrous oxide as a safe and pleasant agent. This was largely superseded by chloroform, discovered much earlier by Liebig and others, but introduced as an anaesthetic in 1847, by Prof. Simpson. This proved to be the most powerful and dangerous of all. Thus the whole policy of the medical profession was to discourage the safe, and encourage the more dangerous agents. The magnetic sleep, the most perfect of all anaesthetic
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