various stages of lupus have been
completed remains unchanged.

The observation of the treatment of lupus with the remedy is so
instructive and must be so convincing as regards the specific nature of
the remedy that every one wishing to occupy himself with the study of
this remedy should if possible make his first experiments with lupus.

Less marked, but still apparent to the eye and touch are the local
reactions in tuberculosis of the lymphatic glands, of the bones and
joints, etc., in which case swelling and increased painfulness, and in
the more superficial parts also a reddening can be observed.

The reaction in the inner organs, especially the lungs is removed from
our observation unless we consider the increased coughing and
expectoration of the patients after the first injection a local
reaction. At the same time we must assume that these parts undergo
changes directly observed in the case of lupus.

The different forms of reaction described have appeared without
exception in previous trials on the dose of .01 ccm. when any form of
tuberculosis prevailed in the system, and therefore I trust that I am
justified in assuming, that in the future this remedy will constitute an
indispensible diagnostic auxiliary. We will be enabled to diagnose in
doubtful cases of phthisis even then, when it is impossible to obtain
reliable information concerning the nature of the ailment, by the
presence of bacilli or elastic fibres in the sputum or by a physical
examination. Glandular affectations, hidden tuberculosis of the bones,
doubtful tuberculosis of the skin and the like will easily and reliably
prove to be such. In case of apparently completed processes of
tuberculosis of the lungs or joints it will be possible to show whether
the process of the disease is in reality a complete one or establish the
existence of centres from which later on the disease may spread like a
fire from a live coal in the ashes.

But much more important are the specific qualities of the remedy than
the aids it offers for the diagnosis.

While describing the changes, that are caused by hypodermic injections
of the remedy, on the parts of the skin affected by lupus, attention was
called to the fact that the lupose tissue does not return to its
original condition after the swelling and reddening have ceased, but is
more or less destroyed and disappears. On some places, as observation
teaches, the process is such, that after a single injection the