ather be explained thus: in the beginning there is an
abundance of living tuberculous tissue and only a minute quantity of the
effective substance is sufficient to cause a strong reaction; through
each injection a certain quantity of this responsive tissue disappears,
and then relatively larger doses are required to cause the same degree
of reaction as before. Aside from this adaptation may assert itself
within certain limits. As soon as the patient is treated with such
increased doses, and that he reacts no more than one not afflicted with
tuberculosis, we may assume that all the reactive tuberculous tissue is
dead. It is then only necessary to continue the treatment at intervals
and with gradually increased doses as long as any bacilli remain in the
system, to protect the patient from a new infection.

It remains to be learnt in the future whether this conception and the
deductions based thereon are correct. For the present I have directed
the manner of application of the remedy on this basis, which in our
experiments resulted as follows:

To begin again with the simplest case, namely lupus, we injected the
full dose of .01 ccm. in nearly all such patients to begin with, and
allowed the reaction to take its full course, after 1-2 weeks we again
injected .01 ccm. and so forth until the reaction became less and less
and finally ceased. In the case of two patients with facial lupus three
respectively four injections in this manner resulted in a clean, smooth
scar in place of the affected parts; the remaining patients of this kind
have also improved in a measure proportioned to the time of treatment.
All the patients have suffered from their afflictions for years and have
been treated by various methods without success.

Tuberculosis of the glands, bones and joints has been treated in a very
similar manner, as in these cases larger doses were applied at longer
intervals. The result was the same as with lupus, a rapid cure in the
lighter and milder cases and a slowly progressing improvement in the
severer ones.

With the majority of our patients, those suffering from pulmonary
consumption, the conditions are somewhat different, patients with
decided pulmonary tuberculosis are very much more responsive to this
remedy, than those afflicted with surgical tubercles. We were forced to
reduce the quantity of the first dose of .01 ccm. as prepared for the
phthisicist, and we found that as a rule he reacted strongly on a dose