, the strength failing.
From this time he lay for more than half an hour nearly in the same
state; the strength was gradually sinking, and as there was no prospect
of recovery, he was killed. In this case, the true apoplectic puffing of
the cheeks was present the greater part of the time.

* * * * *

From the foregoing, and from additional experiments, which it is not
necessary to give in detail, it appeared, that when applied to a wound
made in the most sensitive parts of the integuments, the oil of tobacco,
though it caused a good deal of pain, had a far less general effect than
when applied to the tongue. Rats were less affected than cats. _Two_
and sometimes _three_ drops rubbed upon the tongue of a rat, did not
kill in half an hour.

_Three large_ drops rubbed upon the tongue of a full-sized cat, usually
caused death in from _three_ to _ten_ minutes, and in one instance,
already stated, in _two_ minutes and _forty-five_ seconds. One drop
passed into the jugular vein of a large dog, occasioned an immediate
cry, followed in a few moments by staggering, convulsive twitchings of
the voluntary muscles, and vomiting.

In those cases in which full vomiting occurred, evident relief followed.
Young animals suffered much more than those, which had come to their
full growth and vigor. In those animals, whose lives were suddenly
destroyed by the tobacco, no coagulation of the blood took place. The
bodies of several cats were examined the next day after death, and only
in a single instance was a slight coagulum observed; and this was in a
cat, whose constitution possessed strong powers of resistance, and whose
death was comparatively lingering.

It is not improbable, that the charge of inhumanity may be made against
experiments prosecuted upon defenceless animals, with a poison so
painful and destructive in its operation as tobacco; the justice of this
charge is freely admitted, if such experiments be made merely for the
gratification of curiosity, and not with the object and reasonable hope
of making them useful to mankind, and of influencing, at least, some
few individuals, to abandon the practice (humane can it be called?) of
administering this poison to themselves and their children, till it
occasions disease and death. Indeed, there are but few, who would
willingly witness more than a single experiment of this kind, with no
prospect of benefit to result from it.

When applied to sensit