PERIMENT 5.

In the tip of the nose of a mouse, a small puncture was made with a
surgeon's needle, bedewed with the oil of tobacco. The little animal,
from the insertion of this small quantity of the poison, fell into a
violent agitation, and was dead in six minutes.

EXPERIMENT 6.

Two drops of the oil were rubbed upon the tongue of a red squirrel. This
animal, so athletic as to render it difficult to secure him sufficiently
long for the application, was in a moment seized with a violent agitation
of the whole body and limbs, and was perfectly dead and motionless in
one minute.

EXPERIMENT 7.

To the tongue of a dog rather under the middle size, five drops of the
oil of tobacco were applied. In forty-five seconds he fell upon the
side, got up, retched, and fell again. In one minute the respiration was
laborious, and the pupils were dilated. In two minutes the breathing was
slow and feeble, with puffing of the cheeks. In three minutes the pupils
were smaller but continually varying. The left fore leg and the right
hind leg were affected with a simultaneous convulsion or jerk,
corresponding with the inspiratory motions of the chest. This continued
for five minutes.

In nine minutes alimentary evacuations; symptoms abated; and the animal
attempted to walk. At ten minutes two drops of the oil were applied to
the tongue. Instantly the breathing became laborious, with puffing of
the cheeks; pupils much dilated. The convulsive or jerking motions of
the two limbs appeared as before, recurring regularly at the interval
of about two seconds, and exactly corresponding with the inspirations.
In twelve minutes the pupils were more natural; slight frothing at the
mouth, the animal still lying upon the side. At this time a drop of
the oil was passed into each nostril. The labor of the respiration was
suddenly increased, the jaws locked.

In twenty-two minutes no material change; the jaws were separated and
five drops of the oil were rubbed on the tongue. In one minute the
pupils were entirely dilated, with strong convulsions. In one and an
half minutes, in trying to walk, the animal fell. In three minutes the
eyes rolled up, and convulsions continued. In six minutes, the plica
semilunaris so drawn as to cover half the cornea. In seven minutes,
slight frothing at the mouth. In forty minutes the inspirations were
less deep, the convulsions had been unremitted