s in animals born of
parents in which these ear-alterations had been caused by an injury
to the restiform body near the nib of the calamus.

"'7th. Absence of two toes out of the three of the hind leg, and
sometimes of the three, in animals whose parents had eaten up their
hind-leg toes which had become anaesthetic from a section of the
sciatic nerve alone, or of that nerve and also of the crural.
Sometimes, instead of complete absence of the toes, only a part of
one or two or three was missing in the young, although in the parent
not only the toes but the whole foot was absent (partly eaten off,
partly destroyed by inflammation, ulceration, or gangrene).

"'8th. Appearance of various morbid states of the skin and hair of
the neck and face in animals born of parents having had similar
alterations in the same parts, as effects of an injury to the
sciatic nerve.'

"It should be especially observed that Brown-Sequard had bred during
thirty years many thousand guinea-pigs from animals which had not
been operated upon, and not one of these manifested the epileptic
tendency. Nor has he ever seen a guinea-pig born without toes,
which was not the offspring of parents which had gnawed off their
own toes owing to the sciatic nerve having been divided. Of this
latter fact thirteen instances were carefully recorded, and a
greater number were seen; yet Brown-Sequard speaks of such cases as
one of the rarer forms of inheritance. It is a still more
interesting fact, 'that the sciatic nerve in the congenitally
toeless animal has inherited the power of passing through all the
different morbid states which have occurred in one of its parents
from the time of the division till after its reunion with the
peripheric end. It is not, therefore, simply the power of
performing an action which is inherited, but the power of performing
a whole series of actions, in a certain order.'

"In most of the cases of inheritance recorded by Brown-Sequard only
one of the two parents had been operated upon and was affected. He
concludes by expressing his belief that 'what is transmitted is the
morbid state of the nervous system,' due to the operation performed
on the parents."

Mr. Darwin proceeds to give other instances of inherited effects of
mutilations:--

"With the horse there seems hardly a doubt that exostoses on the
legs, caused by too much travelling on hard roads, are inherited.
Blumenbach records the case of a man who had his litt