which was transmitted from
father to son, the daughters not being affected. Five generations could
be reckoned which had been affected in the manner described.

The "porcupine-man" seen by Baker contracted small-pox, and his skin
was temporarily freed from the squamae, but these reappeared shortly
afterward. There are several older records of prickly men or
porcupine-men. Ascanius mentions a porcupine-man, as do Buffon and
Schreber. Autenreith speaks of a porcupine-man who was covered with
innumerable verrucae. Martin described a remarkable variety of
ichthyosis in which the skin was covered with strong hairs like the
bristles of a boar. When numerous and thick the scales sometimes
assumed a greenish-black hue. An example of this condition was the
individual who exhibited under the name of the "alligator-boy." Figure
286 represents an "alligator-boy" exhibited by C. T. Taylor. The skin
affected in this case resembled in color and consistency that of a
young alligator. It was remarked that his olfactory sense was intact.

The harlequin fetus, of which there are specimens in Guy's Hospital,
London Hospital, and the Royal College of Surgeons Museum, is the
result of ichthyosis congenita. According to Crocker either after the
removal of the vernix caseosa, which may be thick, or as the skin dries
it is noticeably red, smooth, shiny, and in the more severe cases
covered with actual plates. In the harlequin fetus the whole surface
of the body is thickly covered with fatty epidermic plates, about 1/16
inch in thickness, which are broken up by horizontal and vertical
fissures, and arranged transversely to the surface of the body like a
loosely-built stone wall. After birth these fissures may extend down
into the corium, and on movement produce much pain. The skin is so
stiff and contracted that the eyes cannot be completely opened or shut,
the lips are too stiff to permit of sucking, and are often inverted;
the nose and ears are atrophied, the toes are contracted and cramped,
and, if not born dead, the child soon dies from starvation and loss of
heat. When the disease is less severe the child may survive some time.
Crocker had a patient, a male child one month old, who survived three
months. Hallopeau and Elliot also report similar cases.

Contagious follicular keratosis is an extremely rare affection in which
there are peculiar, spine-like outgrowths, consisting in exudations of
the mouths of the sebaceous glands. Leloir