esist all
treatment.

Holston reports a case of chronic singultus of seven years' standing.
It had followed an attack of whooping-cough, and was finally cured
apparently by the administration of strychnin. Cowan speaks of a
shoemaker of twenty-two who experienced an attack of constant singultus
for a week, and then intermittent attacks for six years. Cowan also
mentions instances of prolonged hiccough related by Heberden, Good,
Hoffman, and Wartmouth. Barrett is accredited with reporting a case of
persistent hiccough in a man of thirty-five. Rowland speaks of a man of
thirty-five who hiccoughed for twelve years. The paroxysms were almost
constant, and occurred once or twice a minute during the hours when the
man was not sleeping. There was no noise with the cough. There is
another case related in the same journal of a man who died on the
fourth day of an attack of singultus, probably due to abscess of the
diaphragm, which no remedy would relieve. Moore records a case of a
child, injured when young, who hiccoughed until about twenty years of
age (the age at the time of report). Foot mentions a lad of fifteen
who, except when asleep, hiccoughed incessantly for twenty-two weeks,
and who suffered two similar, but less severe, attacks in the summer of
1879, and again in 1880. The disease was supposed to be due to the
habit of pressing the chest against the desk when at school. Dexter
reports a case of long-continued singultus in an Irish girl of
eighteen, ascribed to habitual masturbation. There was no intermission
in the paroxysm, which increased in force until general convulsions
ensued. The patient said that the paroxysm could be stopped by firm
pressure on the upper part of the external genital organs. Dexter
applied firm pressure on her clitoris, and the convulsions subsided,
and the patient fell asleep. They could be excited by firm pressure on
the lower vertebrae. Corson speaks of a man of fifty-seven who, after
exposure to cold, suffered exhausting hiccough for nine days; and also
records the case of an Irish servant who suffered hiccough for four
months; the cause was ascribed to fright. Stevenson cites a fatal
instance of hiccough in a stone-mason of forty-four who suffered
continuously from May 14th to May 28th. The only remedy that seemed to
have any effect in this case was castor-oil in strong purgative doses.

Willard speaks of a man of thirty-four who began to hiccough after an
attack of pneumonia, and c