to Lewin, there is mentioned in
the case reported by Gauchet a symptom quite unique in the literature
of quinin, viz., hemoptysis. Simon de Ronchard first noted the
occurrence of several cases of hemoptysis following the administration
of doses of eight grains daily. In the persons thus attacked the lungs
and heart were healthy. Hemoptysis promptly ceased with the suspension
of the drug. When it was renewed, blood again appeared in the sputa.
Taussig mentions a curious mistake, in which an ounce of quinin
sulphate was administered to a patient at one dose; the only symptoms
noticed were a stuporous condition and complete deafness. No antidote
was given, and the patient perfectly recovered in a week. In malarious
countries, and particularly in the malarial fevers of the late war,
enormous quantities of quinin were frequently given. In fact, at the
present day in some parts of the South quinin is constantly kept on the
table as a prophylactic constituent of the diet.
Skinner noticed the occurrence of a scarlatiniform eruption in a woman
after the dose of 1/165 grain of strychnin, which, however, disappeared
with the discontinuance of the drug. There was a man in London in 1865
who died in twenty minute's after the ingestion of 1/2 grain of
strychnin. Wood speaks of a case in which the administration of 1/100
grain killed a child three and one-half months old. Gray speaks of a
man who took 22 grains and was not seen for about an hour. He had
vomited some of it immediately after taking the dose, and was
successfully treated with chloral hydrate. A curious case is mentioned
in which three mustard plasters, one on the throat, one on the back of
the neck, and another on the left shoulder of a woman, produced
symptoms similar to strychnin poisoning. They remained in position for
about thirty minutes, and about thirty hours afterward a painful
stinging sensation commenced in the back of the neck, followed by
violent twitching of the muscles of the face, arms, and legs, which
continued in regular succession through the whole of the night, but
after twelve hours yielded to hot fomentations of poppy-heads applied
to the back of the neck. It could not be ascertained whether any
medicine containing strychnin had been taken, but surely, from the
symptoms, such must have been the case.
Tobacco.--O'Neill a gives the history of a farmer's wife, aged forty,
who wounded her leg against a sewing-machine, and by lay advice applied
a han
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