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ts frequency and spread. Syphilis is not restricted to classes by any means; it is not those of the lower class alone who are its victims. Dr. Fr. J. Behrend, in his work, "Die Prostitution in Berlin," observes that abolition of the brothels in that city in 1845, '46, '47 and '48, trebled the number of cases of syphilis treated at the Der Charite; in the year 1848 the cases of syphilis treated at that hospital numbered over 1800. It was also remarked during this period of legally-enforced virtue, that, as inconsistently as it might appear, the disease invaded the best of families. From Dr. Neumann, in his brochure entitled "Die Berliner Syphilisfrage," published in 1852, we learn that, in the Trades and Mechanics' Benevolent Union of Berlin, in 1849, 13.51 per cent. of the sick were so from syphilis. In the thirteenth volume of the _British and Foreign Medico-Chirurgical Review_, we find, in a review of the control of prostitution, an estimate in regard to the syphilization of a nation. The estimates are made on the most conservative figures, as, in the desire of the reviewer not to overestimate, he starts by figuring out the actual number of prostitutes in England, Wales, and Scotland to be only 50,000, when they were estimated, by those who had carefully studied the subject, as being more than double that number; the conservative estimate is, however, suitable for our purpose; so that we cannot be accused of overestimating the results. The portion of the review to which we wish to call attention is as follows:-- "Though the result of the evidence contained in the first report of the commissioners on the constabulary force of England and Wales was that at that time about 2 per cent. of the prostitutes of London were suffering under some form of venereal disease, yet we will descend even lower, and presume that of one hundred healthy prostitutes, taken promiscuously from England and Scotland, if each submits to one indiscriminate sexual act in twenty-four hours, not more than one would become infected with syphilis, an estimate which is without doubt far too low; yet, if admitted to be correct, the necessary consequence will be, _that of the fifty thousand prostitutes five hundred are diseased within the aforesaid twenty-four hours_. "If we next admit that a fifth of these five hundred diseased women are admitted to hospital on the day on which the disease appears, it follows _that there are every day on the str
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