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er life the subjects for cancerous disease as well as furnishing the easiest victims for venereal infection. These warts, although easily removed, have a tendency to recurrence, especially as long as the moist bed that has once grown them there is still vegetating. The prepuce is liable to indurations and hypertrophy. Of the first anomaly, the London _Lancet_ of 1846 has a record of two cases in which paraphimosis was induced in elderly subjects, and of one in which it induced phimosis. Since then a number of cases of thickening and induration have been reported. Hypertrophy may take place in any degree, varying from the mere leathery and overpendulous but unobstructive prepuce to the case recorded by Vidal, in the fifth volume of his "Pathologie Externe et Medecine Operatoire," which happened in the practice of M. Rigal, de Gaillae. The hypertrophied prepuce was something enormous, and hung down to below the patient's knees; it was pear-shaped, with the base hanging downward; this base was as large as a man's head. This prepuce was successfully removed by M. Rigal, who presented the specimen before the Paris Surgical Society, who were then discussing a somewhat similar but not so extensive a case, presented by M. Lenoire. Vidal mentions having operated on a number of cases of this deformity of the prepuce in various degrees of growth. As a rule, simple hypertrophic disease of the penile integument does not interfere with the sexual functions of the male organ after its removal; it being susceptible of complete removal in exaggerated cases, even without touching the body of the organ. There are exceptions to this rule, however, when even this otherwise non-malignant disease may entail the loss of all the genitals. In the London _Lancet_ of July 11, 1846, at page 46, there is a record of a remarkable case of this nature reported by F. H. Brett, Esq., F.R.C.S. The case was that of a locksmith of forty years of age, who was naturally much phimosed. The penis was enormously enlarged, as well as the scrotum, which was more or less ulcerated and full of sinuses filled with a serous pus; some six months prior to the final operation, a part of the prepuce was removed to facilitate urination, but the whole mass had to be subsequently removed, including the whole of the skin of the penis and the scrotum, the testicles having been carefully dissected out and recovered with some skin flap. In this case the disease was believe
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