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ion, is early confronted by a curious fact. It is the ignorance which generally prevails concerning the part borne by the medical profession in exciting public attention to the cruelties of experimentation. The present generation of scientific teachers, of medical students and physicians, are as a rule profoundly ignorant of the beginning of the controversy, and would be as surprised as Professor Osler of Oxford University seems to have been surprised, to hear that medical journals first made known to the world the abuses of vivisection. Remembering how vigorously the physiological laboratory of to-day resists and resents either investigation or criticism, one is forced to confess that rarely, if ever, in the history of the world has a transformation of ideals been more completely attained. If the followers of Wilberforce and Clarkson, to whom the world is indebted for the great impulse against negro slavery, were to-day organized for the exploitation of the negroes on the Congo, or the Indians on the Amazon, or for carrying on the slave-trade secretly, without restriction or supervision, the condition of affairs could hardly be more singular than the dominance obtained by the physiological laboratory upon the medical conscience of to-day. The facts constitute a remarkable chapter of human experience; and though once before they have been stated by the present writer, it is evident, by the evidence given before the Royal Commission, that a vast amount of ignorance yet remains to be dispelled. Up to a period considerably beyond the middle of the last century, the sentiment of the medical profession in England was practically unanimous in condemning the methods of vivisection which prevailed on the Continent of Europe. In 1855 the science of bacteriology was unknown. It is possible that not more than half a dozen English physiologists at that time were making experiments on living animals. It was not even regarded as an essential in the teaching of medical schools. In 1875 some of the most distinguished surgeons and physicians of Great Britain testified before the Royal Commission that as medical students they had never witnessed an experiment on a living animal. That the agitation against the cruelties of vivisectors which made itself evident during the last half of the previous century had no origin in ignorance is easily demonstrated. It was the medical journals of England which first made known to the wor
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