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in House of Castilla and Aragon _Isabel I of Castilla_.--Born at Madrigal de las Altas Torres (Avila), April 22, 1451; daughter of Juan II of Castilla and Isabel of Portugal. Married Fernando II of Aragon, Oct. 18 or 19, 1469. Succeeded her brother Enrique IV on the throne of Castilla and Leon; proclaimed queen Dec. 13, 1474. Died at Medina del Campo (Valladolid), Nov. 26, 1504. Named as her heirs her daughter Juana and the latter's husband, Philip of Austria; and appointed Fernando (now V of Castilla) regent of Castilla and Leon during the minority of Juana's son Carlos. Fernando and Isabel were styled "the Catholic Sovereigns." _Fernando V of Castilla_ (II of Aragon and Navarra).--Born at Sos (Zaragoza), May 10, 1452; son of Juan II and Juana Enriquez of Aragon and Navarra. Died at Madrigalejo, Jan. 23, 1516. During Isabel's life, was king-consort, and governed her dominions only by virtue of this relation; after her death, was regent only of Castilla, which dignity he held until his death, except from June 27, 1506, to Aug. 21, 1507, during which period he retired to Aragon, in favor of Juana's husband Philip. Inheriting the throne of Aragon and Navarra (Jan. 20, 1479), his marriage with Isabel (1469) and their conquest of Granada (1492) united under one monarchy the provinces now comprised in the country of Spain. _Juana_.--Born at Toledo, in 1479; second daughter of Isabel and Fernando. Married Philip of Austria, Oct. 20 or 21, 1496. Died at Tordesillas, April 11, 1555. Reigned from Nov. 26, 1504, until her death--jointly with her husband, during his life; and with her son thereafter--but under her father's regency until 1516; during her reign she was more or less subject to insanity, and was but nominally queen, seldom exercising royal powers, and living in strict seclusion. Known as "la Loca," "the Mad." House of Austria _Felipe I_ (Philip of Austria).--Born at Bruges, July 22, 1478; son of Maximilian I, emperor of Germany, and Maria de Borgona. By his marriage to Juana, was king-consort of Castilla from Nov. 26, 1504, until his death. Died at Burgos, Sept. 25, 1506. Styled "el Hermoso," "the Beautiful." _Carlos I_ (Charles V, emperor of Germany).--Born at Ghent, Feb. 25, 1500; son of Felipe I and Juana. Landed in Spain in 1517. Married Isabel of Portugal (daughter of Manoel), March 11, 1526. Abdicated in favor of his son Felipe II, Jan. 16, 1556; died at monastery of Yuste, Aug. 30, 1558. El
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