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s who was infected with cowpox, into the arm of James Phipps, a healthy boy about eight years of age. This is the first instance of regular inoculation of the vaccine disease by Jenner. The boy went through the disorder, and on July 1st following he had the matter of smallpox introduced into his arm, but no effect followed. Jenner had not before seen the cowpox but as presented on the hands of the milkers, nor had it been transmitted from one human being to another. He was struck with its great resemblance to the smallpox pustule. The success of this case must necessarily have operated powerfully upon him, and have urged him to continue the research with increased energy. His anticipations thus realized, his intentions accomplished, what must have been the feelings of such a man as Jenner? They were suited to the magnitude of the occasion, and mark the character of the philosopher, distinguished as it ever was by great simplicity, benevolence, and humility. "While," says he, "the vaccine discovery was progressive, the joy I felt at the prospect before me of being the instrument destined to take away from the world one of its greatest calamities, blended with the fond hope of enjoying independence and domestic peace and happiness, was often so excessive, that in pursuing my favorite subject among the meadows I have sometimes found myself in a kind of reverie. It is pleasant to me to recollect that these reflections always ended in devout acknowledgments to that Being from whom this and all other mercies flow." Lord Bacon said that "it is Heaven upon earth to have a man's mind move in charity, rest in Providence, and turn upon the poles of truth." Jenner was a striking illustration of the truth of that remark. The modesty of Jenner was evidenced in his original intention of submitting his observations on the cowpox in a paper addressed to the Royal Society. Doctor Baron tells us that "when the subject was laid before the president (the late Sir Joseph Banks), Jenner was given to understand that he should be cautious and prudent; that he had already gained some credit by his communications to the Royal Society and ought not to risk his reputation by presenting to the learned body anything which appeared so much at variance with established knowledge, and withal so incredible." It came forth most unostentatiously, about the end of June, 1798, dedicated to his friend Doctor Parry of Bath. Doctor Jenner visited London in t
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