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o bring forth is, that the substance we are specially dealing with, alcohol, possesses the self-same power. By this influence it produces all those peculiar effects which in every-day life are so frequently illustrated." PARALYZES THE MINUTE BLOOD-VESSELS. It paralyzes the minute blood-vessels, and allows them to become dilated with the flowing blood. "If you attend a large dinner party, you will observe, after the first few courses, when the wine is beginning to circulate, a progressive change in some of those about you who have taken wine. The face begins to get flushed, the eye brightens, and the murmur of conversation becomes loud. What is the reason of that flushing of the countenance? It is the same as the flush from blushing, or from the reaction of cold, or from the nitrite of amyl. It is the dilatation of vessels following upon the reduction of nervous control, which reduction has been induced by the alcohol. In a word, the first stage, the stage of vascular excitement from alcohol, has been established." HEART DISTURBANCE. "The action of the alcohol extending so far does not stop there. With the disturbance of power in the extreme vessels, more disturbance is set up in other organs, and the first organ that shares in it is the heart. With each beat of the heart a certain degree of resistance is offered by the vessels when their nervous supply is perfect, and the stroke of the heart is moderated in respect both to tension and to time. But when the vessels are rendered relaxed, the resistance is removed, the heart begins to run quicker, like a watch from which the pallets have been removed, and the heart-stroke, losing nothing in force, is greatly increased in frequency, with a weakened recoil stroke. It is easy to account, in this manner, for the quickened heart and pulse which accompany the first stage of deranged action from alcohol, and you will be interested to know to what extent this increase of vascular action proceeds. The information on this subject is exceedingly curious and important." * * * * * "The stage of primary excitement of the circulation thus induced lasts for a considerable time, but at length the heart flags from its overaction, and requires the stimulus of more spirit to carry it on in its work. Let us take what we may call a moderate amount of alcohol, say two ounces by volume, in form of wine, or beer, or spirits. What is called strong
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