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ranous or capsular structure of the organ, upon which, it acts to prevent the proper dialysis and free secretion. The organ, at first, becomes large from the distention of its vessels, the surcharge of fluid matter and the thickening of tissue. After a time, there follows contraction of membrane, and slow shrinking of the whole mass of the organ in its cellular parts. Then the shrunken, hardened, roughened mass is said to be 'hob-nailed,' a common, but expressive term. By the time this change occurs, the body of him in whom it is developed is usually dropsical in its lower parts, owing to the obstruction offered to the returning blood by the veins, and his fate is sealed.... Again, under an increase of fatty substance in the body, the structure of the liver may be charged with, fatty cells, and undergo what is technically designated fatty degeneration." HOW THE KIDNEYS SUFFER. "The kidneys, also, suffer deterioration. Their minute structures undergo fatty modification; their vessels lose their due elasticity of power of contraction; or their membranes permit to pass through them the albumen from the blood. This last condition reached, the body loses power as if it were being gradually drained even of its blood." CONGESTION OF THE LUNGS. "The vessels of the lungs are easily relaxed by alcohol; and as they, of all parts, are most exposed to vicissitudes of heat and cold, they are readily congested when, paralyzed by the spirit, they are subjected to the effects of a sudden fall of atmospheric temperature. Thus, the suddenly fatal congestions of lungs which so easily befall the confirmed alcoholic during the severe winter seasons." ORGANIC DETERIORATIONS OF THE HEART. The heart is one of the greatest sufferers from alcohol. Quoting again from Dr. Richardson: "The membranous structures which envelope and line the organ are changed in quality, are thickened, rendered cartilaginous and even calcareous or bony. Then the valves, which are made up of folds of membrane, lose their suppleness, and what is called valvular disease is permanently established. The coats of the great blood-vessel leading from the heart, the aorto, share, not unfrequently, in the same changes of structure, so that the vessel loses its elasticity and its power to feed the heart by the recoil from its distention, after the heart, by its stroke, has filled it with blood. "Again, the muscular structure of the heart fails, owing to de
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