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lt to know with certainty when Hill first became interested in the herb. He mentions it in passing in _The British Herbal_ (1756), I, 526 and may have sold it as early as 1742 when he opened an apothecary shop. [16] Reid's dissertation at Edinburgh, entitled _De Insania_ (1798), contains materials on the relationship of the imagination to all forms of mental disturbance. Secondary literature on hypochondria is plentiful. Works include: R. H. Gillespie, _Hypochondria_ (London, 1928), William K. Richmond, _The English Disease_ (London, 1958), Charles Chenevix Trench, _The Royal Malady_ (New York, 1964), and Ilza Vieth, _Hysteria: The History of a Disease_ (Chicago, 1965), and "On Hysterical and Hypochondriacal Afflictions," _Bulletin of the History of Medicine_, XXX (1956), 233-40. [17] Joseph Spence, _Observations, Anecdotes, and Characters of Books and Men_, ed. James M. Osborn (Oxford, 1966), I, 264. I am indebted to A. D. Morris, M.D., F.R.S.M., for help of various sorts in writing this introduction. BIBLIOGRAPHICAL NOTE The text of this facsimile of _Hypochondriasis_ is reproduced from a copy in the Library of the Royal Society of Medicine, London. HYPOCHONDRIASIS. A PRACTICAL TREATISE, &c. HYPOCHONDRIASIS. SECT. I. The NATURE of the DISORDER. To call the Hypochondriasis a fanciful malady, is ignorant and cruel. It is a real, and a sad disease: an obstruction of the spleen by thickened and distempered blood; extending itself often to the liver, and other parts; and unhappily is in England very frequent: physick scarce knows one more fertile in ill; or more difficult of cure. The blood is a mixture of many fluids, which, in a state of health, are so combined, that the whole passes freely through its appointed vessels; but if by the loss of the thinner parts, the rest becomes too gross to be thus carried through, it will stop where the circulation has least power; and having thus stopped it will accumulate; heaping by degrees obstruction on obstruction. Health and chearfulness, and the quiet exercise of mind, depend upon a perfect circulation: is it a wonder then, when this becomes impeded the body looses of its health, and the temper of its sprightliness? to be otherwise would be the miracle; and he inhumanly insults the afflicted, who calls all this a voluntary frowardness. Its slightest state brings with it sickness, anguish and oppression; and
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