conjungi."[3]

[Footnote 3: Leeuwenhoek, _Arcana Naturae Detecta._ Ed. Nov., 1721.]

Thus Leeuwenhoek discovered that yeast consists of globules floating in a
fluid; but he thought that they were merely the starchy particles of the
grain from which the wort was made, rearranged. He discovered the fact
that yeast had a definite structure, but not the meaning of the fact. A
century and a half elapsed, and the investigation of yeast was
recommenced almost simultaneously by Cagniard de la Tour in France, and
by Schwann and Kuetzing in Germany. The French observer was the first to
publish his results; and the subject received at his hands and at those
of his colleague, the botanist Turpin, full and satisfactory
investigation.

The main conclusions at which they arrived are these. The globular, or
oval, corpuscles which float so thickly in the yeast as to make it muddy,
though the largest are not more than one two-thousandth of an inch in
diameter, and the smallest may measure less than one seven-thousandth of
an inch, are living organisms. They multiply with great rapidity by
giving off minute buds, which soon attain the size of their parent, and
then either become detached or remain united, forming the compound
globules of which Leeuwenhoek speaks, though the constancy of their
arrangement in sixes existed only in the worthy Dutchman's imagination.

It was very soon made out that these yeast organisms, to which Turpin
gave the name of _Torula cerevisioe_, were more nearly allied to the
lower Fungi than to anything else. Indeed Turpin, and subsequently
Berkeley and Hoffmann, believed that they had traced the development of
the _Torula_ into the well-known and very common mould--the _Penicillium
glaucum_. Other observers have not succeeded in verifying these
statements; and my own observations lead me to believe, that while the
connection between _Torula_ and the moulds is a very close one, it is of
a different nature from that which has been supposed. I have never been
able to trace the development of _Torula_ into a true mould; but it is
quite easy to prove that species of true mould, such as _Penicillium_,
when sown in an appropriate nidus, such as a solution of tartrate of
ammonia and yeast-ash, in water, with or without sugar, give rise to
_Toruloe_, similar in all respects to _T. cerevisioe_, except that they
are, on the average, smaller. Moreover, Bail has observed the development
of a _Torula_ larger than _T. cer