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hemselves, must either become inactive and weak, or work upon themselves and become diseased. But let the situation of such persons be changed; bring them, for instance, from the listlessness of retirement to the business and bustle of a city; give them a variety of imperative employments, and place them in society so as to supply to their cerebral organs that extent of exercise which gives health and vivacity of action, and in a few months the change produced will be surprising. Health, animation, and acuteness will take the place of former insipidity and dullness. In such instances, it would be absurd to suppose that it is the _mind itself_ which becomes heavy and feeble, and again revives into energy by these changes in external circumstances. The effects arise entirely from changes in the state of the _brain_, and the mental manifestations and the bodily health have been improved solely by the improvement of its condition. The evils arising from excessive or ill-timed exercise of the brain, or any of its parts, are numerous, and equally in accordance with the ordinary laws of physiology. When we use the eye too long or in too bright a light, it becomes bloodshot, and the increased action of its vessels and nerves gives rise to a sensation of fatigue and pain requiring us to desist. If we turn away and relieve the eye, the irritation gradually subsides, and the healthy state returns; but if we continue to look intently, or resume our employment before the eye has regained its natural state by repose, the irritation at last becomes permanent, and disease, followed by weakness of sight, or even blindness, may ensue, as often happens to glass-blowers, smiths, and others who are obliged to work in an intense light. Precisely analogous phenomena occur when, from intense mental excitement, the brain is kept long in a state of excessive activity. The only difference is, that we can always see what happens in the eye, but rarely what takes place in the brain. Occasionally, however, cases of fracture of the skull occur, in which, part of the bone being removed, we _can see_ the quickened circulation in the vessels of the brain as easily as in those of the eye. Sir Astley Cooper had a young gentleman brought to him who had lost a portion of his skull just above the eyebrow. "On examining the head," says Sir Astley, "I distinctly saw that the pulsation of the brain was regular and slow; but at this time he was agitated by
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