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fig. 77) transformed into normal 'up' response, after continuous stimulation, T.] On placing the three sets of records--nerve, tin, and platinum--side by side, it will be seen how essentially similar they are in every respect.[17] This reversion to normal is seen to have appeared in a pronounced manner after rapidly continuous stimulation, in process of which the modified molecular condition must in some way have reverted to the normal. [Illustration: FIG. 78.--THE GRADUAL TRANSITION FROM ABNORMAL TO NORMAL RESPONSE IN PLATINUM The transition will be seen to have commenced at the third and ended at the seventh, counting from the left.] Being desirous to trace this change gradually taking place, I took a platinum wire cell giving modified responses, and obtained a series of records of effects of individual stimuli continued for a long time. In this series, the points of transition from modified response to normal will be clearly seen (fig. 78). [Illustration: FIG. 79.--THE NORMAL RESPONSE _a_ IN NERVE ENHANCED TO _b_ AFTER CONTINUOUS STIMULATION T (WALLER) The normal response in nerve is recorded 'down.'] [Illustration: FIG. 80.--ENHANCED RESPONSE IN PLATINUM AFTER CONTINUOUS STIMULATION T] #Increased response after continuous stimulation.#--We have seen that responses to uniform stimuli sometimes show a staircase increase, apparently owing to the gradual removal of molecular sluggishness. Possibly analogous to this is the increase of response in nerve after continuous stimulation or tetanisation, observed by Waller (fig. 79). Like the staircase effect, this contravenes the commonly accepted theory of the dissimilation of tissue by stimulus, and the consequent depression of response. It is suggested by Waller that this increase of response after tetanisation may be due to the hypothetical evolution of CO_2 to which allusion has previously been made. [Illustration: FIG. 81.--ENHANCED RESPONSE IN TIN AFTER CONTINUOUS STIMULATION T] But there is an exact correspondence between this phenomenon and that exhibited by metals under similar conditions. I give here two sets of records (figs. 80, 81), one obtained with platinum and the other with tin, which demonstrate how the response is enhanced after continuous stimulation in a manner exactly similar to that noticed in the case of nerve. The explanation which has been suggested with regard to the staircase effect--increased molecu
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