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ast eyes, and lofty intellectual forehead which are conspicuous in his later portraits. He was steady in conduct, serious in manner, precise in his way of expressing himself; and while these qualities helped him in the mental application which was so necessary if he was to profit by his student days, he needed a little shaking up in order to adapt himself to the ways of other men in the sphere of active life. This was given him by the constant activities of the hospital, and by the demands which the various societies made upon him; but he did not allow them to interfere with his own researches, for which he could find time when others were overwhelmed by the routine of their daily tasks. His first bit of original research is of special interest because it connects him with his father's work. He made special observations with the microscope of the muscular tissue of the iris of the eye, illustrated his paper by delicate drawings of his own, and published it in the leading microscopical journal. This and a subsequent paper on the phenomena of 'Goose-skin' attracted some attention among physiologists at home and abroad, and brought him into friendly relations with a German professor of world-wide reputation. They also gave great satisfaction to his father and to his favourite teacher Sharpey. But Lister's development henceforth was to take place on Scottish ground, and his visit to Edinburgh in 1853 shaped the whole course of his career. James Syme, under whose influence he thus came, was the most original and brilliant surgeon then living in the British Isles, perhaps in all Europe. His merits as a lecturer were somewhat overshadowed by his extraordinary skill as an operator; but he was a remarkable man in all ways, and the fact that Lister was admitted, first to his lecture-room and operating theatre, and then to his home, was without doubt the happiest accident in his life. The atmosphere of Edinburgh with its large enthusiastic classes in the hospitals, its cultivated and intellectual society outside, supplied just what was wanted to foster the genius of a young man on the threshold of his career. In London, centres of culture were too widely diffused, indifference and apathy too prevalent, conservatism in principles and methods too strongly entrenched. In his new home in the north Lister could watch the boldest operator in his own profession, and could daily meet men scarcely less distinguished in other sciences,
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