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ready in 1860 a population of 390,000. Its streets were narrow, its houses often insanitary. In the haste to make money its citizens had little time to think of air and open spaces. The science of town-planning was unborn. Its hospital, far from having any special advantage of position, was exposed to peculiar dangers. It lay on the edge of the old cathedral graveyard, where the victims of cholera had received promiscuous pit-burial only ten years before. The uppermost tier of a multitude of coffins reached to within a few inches of the surface. These horrors have long been swept away; but, when Lister took charge of his wards in the Infirmary, they were infected by the poisonous air generated so close at hand, and in consequence they presented a gruesome appearance. The patients came from streets which often were foul with dirt, smoke, and disease, and were admitted to gloomy airless wards, where pyaemia or gangrene were firmly established. In such an environment certain death seemed to await them. Though his heart must have sunk within him, Lister set himself bravely to the task of fighting these grim adversaries. For two years, indeed, he was chiefly occupied with routine work and practical improvements; but he continued his speculations, and in 1861 an article on amputations which he contributed to the _System of Surgery_, a large work in four volumes published in London, showed that he had not lost his power of surveying questions broadly and examining them with a fresh and original insight. He was not in danger of letting his mind be swamped with details, but could put them in their place and subordinate them to principles; and his article is chiefly directed to a philosophical survey which would enable his readers to go through the same process of education which he had followed out for himself. Sir Hector Cameron, the most constant of his Glasgow disciples, once illustrated this philosophic spirit from a passage in Cicero contrasting the many scientists who 'render themselves familiar with the strange' (not realizing that it is strange or needs explanation) with the few who 'render themselves strange to the familiar'--who stand away from the phenomena to which every one has become too accustomed and examine them afresh for themselves. In Lister he recognized the peculiar gift which enabled him to rise superior to his subject, and to interpret what was to his colleagues a sealed book. In these days, among the too
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