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of the smaller branches, as it dries, curls up, forming "quills," the thicker masses from the stems constituting the "flat" bark of commerce. The drying, packing and transport of the bark are all operations of a laborious description conducted under most disadvantageous conditions. The enormous medicinal consumption of these barks, and the wasteful and reckless manner of procuring them in America long ago, caused serious and well-grounded apprehension that the native forests would quickly become exhausted. The attention of European communities was early directed to the necessity of securing steady and permanent supplies by introducing the more valuable species into localities likely to be favourable to their cultivation. The first actual attempt to rear plants was made in Algeria in 1849; but the effort was not successful. In 1854 the Dutch government seriously undertook the task of introducing the trees into the island of Java, and an expedition for that purpose was fitted out on an adequate scale. Several hundreds of young trees were obtained, of which a small proportion was successfully landed and planted in Java; and as the result of great attention the cultivation of cinchona plantations in that island became highly prosperous and promising. The desirability of introducing cinchonas into the East Indies was urged in a memorial addressed to the East India Company between 1838 and 1842 by Sir Robert Christison and backed by Dr Forbes Royle; but no active step was taken till 1852, when, again on the motion of Dr Royle, some efforts to obtain plants were made through consular agents. In the end the question was seriously taken up, and Sir Clements R. Markham was appointed to head an expedition to obtain young trees from South America and convey them to India. The transference of the plants was attended with considerable difficulty, but in 1861 under his superintendence a consignment of plants was planted in a favourable situation in the Nilgiri Hills. For several years subsequently additional supplies of plants of various species were obtained from different regions of South America, and some were also procured from the Dutch plantations in Java. Now the culture has spread over a wide area in southern India, in Ceylon, on the slopes of the Himalayas, and in British Burma, and has become widely spread through the tropics generally. The species grown are principally _Cinchona officinalis, C. Calisaya, C. succirubra, C.
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