and its results:
April 12 52% pseudo-eos. 10% lymphocytes counted.
Sept. 2 (one month
after the operation) 22% " 53% " "
By the aid of the comparative surface, these figures were supplemented
by the following averages. On each surface used for comparison were
found:
April 12 38 white = 19.8 pseudo-eos. 10.6 lymphocytes.
Sept. 2 81 " 18.0 " 46.9 "
From this example it follows without doubt, that the =total number of the
white blood corpuscles had about doubled itself=, but that in this
increase the lymphocytes exclusively were concerned, and the
pseudo-eosinophil cells had not undergone the smallest increase.
The results which Kurloff obtained by means of this method in animals
whose spleens had been removed, may be illustrated by one of his
original researches and its accompanying chart and table.
Exp. I. Young female, weight 234 gr. Number of red corpuscles
in a cubic millimeter of blood 5,780,000. Number of white
10,700. On April 19, 1888, the spleen was removed, the wound
healed by first intention. The results of the further
investigation of the blood are found in the following table.
From the chart and table, the number on the surface of
comparison of the white blood corpuscles is seen to have more
than doubled itself in the first seven months, and that this
increase was solely dependent on the flooding of the blood by
lymphocytes. The nucleated or bone-marrow elements and the
large mononuclear cells remained continuously at the same level
during the whole period. The changes in the percentage
proportions ran somewhat differently. The percentages rose from
35 to 66% for the lymphocytes only, whilst for the other forms
they distinctly fell: for the nucleated from 44% to 22% and for
the large mononuclear from 18% to 9%. It was only in the course
of the second year that a very considerable relative and
absolute increase of the eosinophil cells appeared: the values
rose gradually from about 1.0% to 28.9% or from 0.5 to 13.9 on
each comparison area. The last examination of the blood in this
animal was made on April 30, 1890, that is, two years after the
removal of the spleen. The animal was quite healthy, bore four
healthy young guinea-pigs by a father whose spleen had been
removed. The young have a completely normal spleen,
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