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eismann came to believe that the apportionment of the nuclear substance, though quantitatively impartial, is sometimes radically uneven in quality; in particular, that the first bisection of the egg-cell, which marks the beginning of embryonic development, produces two cells utterly different in potentiality, the one containing the "body plasm," which is to develop the main animal structures, the other encompassing the "germ plasm," by which the racial integrity is [to be preserved. Throughout the life of the individual, he believed, this isolation continued; hence the assumed lack of influence of acquired bodily traits upon the germ plasm and its engendered offspring. Hence, also, the application of the microscopical discovery to the deepest questions of human social evolution. Every one will recall that this theory, born of the laboratory, made a tremendous commotion in the outside world. Its application to the welfare and progress of humanity gave it supreme interest, and polemics unnumbered were launched in its favor and in its condemnation. Eager search was made throughout the fields of botany and zoology for new evidence pro or con. But the definitive answer came finally from the same field of exploration in which the theory had been originated--the world of the cell--and the Marine Biological Laboratory was the seat of the new series of experiments which demonstrated the untenability of the Weismannian position. Most curious experiments they were, for in effect they consisted of the making of two or more living creatures out of one, in the case of beings so highly organized as the sea-urchins, the little fishlike vertebrate, amphioxus, and even the lower orders of true fishes. Of course the division of one being to form two is perfectly familiar in the case of those lowly, single-celled creatures such as the protozoa and the bacteria, but it seems quite another matter when one thinks of cutting a fish in two and having two complete living fish remaining. Yet this is virtually what the biologists did. Let me hasten to add that the miraculous feat was not accomplished with an adult fish. On the contrary, it is found necessary to take the subject quite at the beginning of its career, when it consists of an egg-cell in the earliest stages of proliferation. Yet the principle is quite the same, for the adult organism is, after all, nothing more than an aggregation of cells resulting from repeated divisions (growth a
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