imal Industry,
obtained 3 very virulent cultures of tubercle bacilli from the human
subject. A goat inoculated subcutaneously with 1 of these cultures died in
37 days with miliary tuberculosis of the lungs involving the axillary and
prescapular glands. This bacillus was obtained from the mesenteric gland of
a boy. Of still greater interest is a bacillus isolated by Mohler from
human sputum. A goat inoculated subcutaneously with a culture of this germ
died in 95 days of pulmonary tuberculosis. A cat inoculated in the same
manner died in 23 days of generalized tuberculosis. A rabbit similarly
inoculated died in 59 days of pulmonary tuberculosis. Another rabbit
inoculated with a bovine culture for comparison lived 10 days longer than
the one inoculated with this sputum germ. Mohler also inoculated
subcutaneously a 1-year-old heifer with a culture derived from the
tuberculosis mesenteric gland of a boy 4 years of age. This culture was
always refractory in its growth under artificial conditions, and the
bacilli were short, stubby rods, corresponding in appearance to the bovine
type. At the autopsy, held 127 days after the inoculation, the general
condition was seen to be poor and unthrifty, and large, hard tumors were
found at the points of inoculation. On the right side the swelling measured
3-1/2 by 5 inches, and the corresponding lymph gland was 2-3/4 inches long
by 1-3/4 inches in diameter. This gland contained numerous calcareous foci;
one at the apex was an inch in diameter. The lesions on the left shoulder
of the animal were very similar to those found on the right side, but the
dimensions of the tumor were slightly less. The lungs presented an
irregular mass of tuberculous nodules, and 7 or 8 grapelike nodules were
seen on the parietal pleura. Bronchial and mediastinal lymph glands
contained numerous tuberculous foci, and the pericardium, peritoneum,
spleen, and liver also were affected.

In order to throw some light, if possible, upon the morphological constancy
of the different types of tubercle bacilli, Mohler made comparative studies
of bacilli from various sources, and which had been passed through various
species of animals, by making the cultures upon dog serum after the method
described by Theobald Smith. Some important results have been obtained. One
culture of human bacilli which had morphological and cultural peculiarities
similar to those of the bovine bacillus, and which produced only local
lesions in cat