y dark blood.
The walls of both ventricles were much thickened. The valvular structure
of the auricles was congested and granular. The lungs were removed from
the chest with difficulty, owing to the very general pleuritic
adhesions. Both exhibited extensive emphysema. In dividing the lungs,
and tracing the bronchial ramifications, each lobe was found to contain
clusters of enlarged and indurated bronchial glands, impacted with thick
black matter; and prosecuting the investigations, the minute lymphatic
glands were observed clustered in a similar manner, and containing black
fluid. In the substance of the upper lobe of both lungs, the bronchial
glands were of a bright black colour; they were particularly large, and
so numerous as to press considerably upon and obstruct several of the
bronchial tubes. In fact the upper lobe of both lungs exhibited the
plum-pudding structure. At the bifurcation and back part of the trachea,
the bronchial glands were numerous, and of a deep black colour. A
considerable mass of the glandular structure was removed for chemical
and microscopic examination.

The second case was that of a boy aged six years, who was under
treatment for an affection of the heart and kidneys, and who died
apparently from disease of these organs. He was, during his whole life,
of a relaxed and weakly constitution, exceedingly sallow in the
complexion, with a very deep blue tint of the sclerotic coat of the eye.
In the course of the post-mortem examination, there was discovered, in
the lower and lateral part of the right pleura, a cyst containing about
an ounce of semi-fluid melanotic matter; and also the morbid secretion
presented the stratified appearance described by Dr Carswell in his
article upon Melanosis, extending over the inferior half of the costal
pleura and the corresponding part of the diaphragm. It formed a distinct
layer on the surface of the serous membrane, resembling ink or blacking,
and could with difficulty be removed. The black deposit resembled much
in appearance the foreign matter found in the pulmonary organs of the
coal-miner, and therefore was submitted, as well as the bronchial
glands in the other case, to chemical analysis, with the view of
ascertaining if there existed any analogy in the component parts of
each.

Dr Douglas Maclagan submitted both these substances to the action of
concentrated nitric acid, and the results were, that the glandular
structure of the chimney sweep containe